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Carpetia Teppich Design Teppich creme, Gr. 160 cm x 220 cm x 19 mm
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In addition to direct effects of reduced PAR gene dosage, other mechanisms linked to the pathogenesis of TS include disruption of X chromosome genes that have a knock-on (or “ripple”) effect on other parts of the X chromosome itself 2,20,21 , including important non-coding RNAs such as JPX (a key regulator of the X inactivation gene, XIST ) 20,26,30 , or X chromosome genes that influence autosomal genes with regulatory functions such as ubiquitination, chromatin modification, translation, splicing, DNA methylation and circular RNA generation 2,20,21,26,28,29,30,31,32
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